Biologicals are medications that are made using living organisms or their products. Biologicals are vaccines, cultures and other preparations made from living organisms and their products, intended for use in diagnosing, immunizing, or treating humans or animals, or in related research. Biologicals are used for the treatment of psoriasis, biologics are available that specifically target the immune system and help lessen the symptoms of the disease.

The biologics can be used to refer to a wide range of biological products in medicine. However, in most cases, the term "biologics" is used more restrictively for a class of medications (either approved or in development) that are produced by means of biological processes involving recombinant DNA technology. Many biological medications are used for the treatment of chronic diseases, such as rheumatoid arthritis or inflammatory bowel disease, or for the treatment of otherwise untreatable cancer during the remainder of life.